Princeton, NJ — US-China Biopharma

Catalyzing US‑China
Biotech & Pharma
Partnerships

BioRich International connects leading pharmaceutical companies and biotech innovators across the US-China corridor — facilitating licensing deals, capital connections, and R&D collaboration.

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Years of Experience
About BioRich

A Trusted Partner at the
Intersection of East and West

Founded by John Xu, MD, MBA, MS — with over 30 years of experience at Bristol Myers Squibb, Wyeth, WuXi AppTec, and CrownBio — BioRich International operates at the nexus of US and Chinese biopharma. We bridge the information, relationship, and cultural gaps that prevent high-potential deals from closing.

Our network encompasses 250+ Chinese biotech clients, direct relationships with BD&L leadership at 25+ multinational corporations, and active engagement with more than 10 US venture capital firms.

Meet our leadership
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The biggest obstacle to deal-making is not interest or capital — it is information asymmetry. BioLink Weekly exists to close that gap.

John Xu, MD, MBA, MS

Founder & President, BioRich International

BioLink Weekly

Intelligence for US-China Biopharma Dealmakers

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Issue 13July 7, 2026

AstraZeneca Returns to CSPC in a $1.77B siRNA Kidney Pact as Takeda Bets Up to $600M on Insilico's AI Discovery Engine

The June 30 to July 7 window was carried by two China-linked platform licenses rather than clinical-asset buyouts. AstraZeneca went back to its go-to Chinese partner CSPC Pharmaceutical (announced July 3) in a collaboration worth up to $1.77B - $30M upfront, up to $540M in development and regulatory milestones and up to $1.2B in commercial milestones - to discover siRNA therapies for two undisclosed chronic kidney-disease pathways, with extrahepatic (renal) delivery as the technical frontier. A day earlier (July 2), Takeda signed an AI drug-discovery pact with Hong Kong-based Insilico Medicine worth up to about $600M (about $60M in project-initiation and near-term payments plus later milestones and tiered royalties), with Insilico's Pharma.AI platform leading early discovery and Takeda taking worldwide rights to selected candidates. No major M&A (control transaction) was announced in-window, following a heavy late-June cluster. On the science side, the FDA approved Orca Bio's Tregzi (Orca-T) as the first precision-engineered cell therapy for allogeneic transplant (June 30) and expanded Vertex/CRISPR's Casgevy to children aged 2 and older with sickle cell disease (July 1), with Vera Therapeutics' atacicept facing a July 7 FDA decision in IgA nephropathy.

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Issue 12June 30, 2026

China's YolTech Anchors a $230M US Gene-Editing Launch as CARsgen Wins the World's First Solid-Tumor CAR-T Approval

The June 23-30 window paired one marquee China-out license with a landmark China approval. Shanghai-based YolTech Therapeutics out-licensed SERP-01 - an in vivo base-editing therapy for alpha-1 antitrypsin deficiency - to newly launched US company Serapha Bio, taking upfront cash, a minority equity stake, and more than $2B in milestone eligibility while keeping Greater China rights; Serapha debuted via a ~$230M private placement (RA Capital, RTW) and a reverse merger into Boundless Bio (June 23). Novartis added a discovery-stage oncology pact with Scorpion spinout Antares ($105M upfront, up to $1.8B; June 24). On the science side, China's NMPA approved CARsgen's satri-cel as the world's first CAR-T for a solid tumor (June 24), and the FDA approved Viridian's Lumvoa for thyroid eye disease with a class-first active-plus-chronic label (June 26), against a backdrop of three FDA decision reversals on previously rejected cell and gene therapies.

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Issue 11June 23, 2026

Antengene Hands MPM-Backed K2 a CDH6xCD3 TCE in a ~$1B China-Out Deal; Lilly and Biogen Add Bolt-Ons as the FDA Clears the First Oral Carbapenem

The June 16-23 window restarted the China-out licensing engine after two M&A-led weeks. Antengene granted MPM BioImpact-established K2 Therapeutics exclusive ex-Greater China rights to ATG-106, a preclinical CDH6xCD3 bispecific T-cell engager, for about $20M upfront and near-term plus up to $960.5M in milestones (announced June 22), with an option on a second undisclosed TCE on similar terms. Two US bolt-on acquisitions rounded out dealmaking - Eli Lilly's purchase of non-opioid pain developer 4E Therapeutics (undisclosed, June 16) and Biogen's up-to-$1B acquisition of immunology biotech RayThera (June 17). On the science side, the FDA approved Spero/GSK's Utebzi (tebipenem pivoxil), the first oral carbapenem (June 17); MoonLake reported strong Week 52 VELA data for sonelokimab in hidradenitis suppurativa (June 21); and Definium's single-dose lysergide ODT (DT120) met its Phase 3 primary endpoint in major depression (June 22).

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